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The SCS microinjector and its drug distribution pattern. (A) The SCS microinjector comprises a 30-gauge microneedle with length markings (e.g., 900 μm and 1100 μm), a conjunctiva-compressing hub, barrel grips, capacity markings, and a plunger handle for precise fluid delivery. (B) Schematic of drug distribution following suprachoroidal administration. The microneedle delivers therapeutics into the suprachoroidal space (SCS), with the green-highlighted area indicating circumferential drug distribution within this compartment (between the sclera and choroid).

Journal: Frontiers in Medicine

Article Title: Suprachoroidal injection in the treatment of diabetic macular edema: mechanisms, clinical advances, and future perspectives

doi: 10.3389/fmed.2026.1797383

Figure Lengend Snippet: The SCS microinjector and its drug distribution pattern. (A) The SCS microinjector comprises a 30-gauge microneedle with length markings (e.g., 900 μm and 1100 μm), a conjunctiva-compressing hub, barrel grips, capacity markings, and a plunger handle for precise fluid delivery. (B) Schematic of drug distribution following suprachoroidal administration. The microneedle delivers therapeutics into the suprachoroidal space (SCS), with the green-highlighted area indicating circumferential drug distribution within this compartment (between the sclera and choroid).

Article Snippet: The development of SCS drug delivery has achieved a major translational milestone with the FDA approval of Clearside Biomedical’s SCS Microinjector ® ( ).

Techniques: